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Cardiovascular

Mean Arterial Pressure (MAP)

Calculate mean arterial pressure from systolic and diastolic blood pressure.

When to use: MAP is the time-averaged driving pressure for organ perfusion throughout the cardiac cycle. A MAP ≥65 mmHg is the resuscitation target in septic shock (Surviving Sepsis Campaign). It is monitored continuously via arterial lines in ICU patients and guides vasopressor titration (noradrenaline first-line).
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Formula
MAP = (SBP + 2 × DBP) / 3
Key Points for NEET PG
  • Formula: MAP = (SBP + 2×DBP) / 3, because diastole occupies approximately 2/3 of the cardiac cycle.
  • Minimum MAP for adequate cerebral, renal, and coronary perfusion is ~65–70 mmHg.
  • Septic shock definition (Sepsis-3): vasopressor required to maintain MAP ≥65 mmHg AND serum lactate >2 mmol/L.
  • Cerebral Perfusion Pressure (CPP) = MAP − ICP; target CPP ≥60–70 mmHg in TBI management.
  • Pulse pressure (SBP−DBP) narrows in cardiac tamponade and aortic stenosis — a separate high-yield concept.
References
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 · Intensive Care Med (2021)
Guyton AC, Hall JE. Textbook of Medical Physiology (2020)

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