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Steroid Conversion Calculator

Converts between equivalent anti-inflammatory doses of corticosteroids.

When to use: Used when switching between corticosteroids — either to change route, reduce mineralocorticoid effect, or improve dosing practicality. Equivalencies are based on anti-inflammatory potency; mineralocorticoid effects differ significantly.
Calculator

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Formula
Equivalent anti-inflammatory doses (relative to Hydrocortisone 20mg): Hydrocortisone 20mg = Prednisone 5mg = Prednisolone 5mg = Methylprednisolone 4mg = Dexamethasone 0.75mg = Betamethasone 0.75mg = Triamcinolone 4mg = Cortisone 25mg
Key Points for NEET PG
  • Dexamethasone has the highest anti-inflammatory potency and virtually no mineralocorticoid activity
  • Hydrocortisone has significant mineralocorticoid activity — used for adrenal insufficiency replacement
  • Stress dose steroids in adrenal insufficiency: Hydrocortisone 100mg IV bolus, then 50mg Q6H
  • Dexamethasone used in raised ICP, ARDS (RECOVERY trial), meningitis, croup
  • Equivalency is for anti-inflammatory effect only — half-lives and routes differ significantly
References
Clinical Pharmacology of Corticosteroids · Annals of the New York Academy of Sciences (1995)
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